Dr Anna Herman-Antosiewicz (PhD, DSc)

Scientific interests:


Publications:

  • Herman-Antosiewicz A., Powolny A.A., Singh S.V. (2007) Molecular targets of cancer chemoprevention by garlic-derived organosulfides. Acta Pharmacol. Sin. 28:1355-64
  • Antosiewicz J., Ziolkowski W., Kaczor J.J., Herman-Antosiewicz A. (2007) Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool. Free Radic. Biol. Med. 43: 265-70.
  • Herman-Antosiewicz A., Lew K.L., Xiao H., Singh S.V. (2007) Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line. Mol. Cancer Ther. 6: 1673-81.
  • Herman-Antosiewicz A., Stan S.D., Hahm E.R., Xiao D., Singh S.V. (2007) Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic. Mol. Cancer Ther. 6:1249-61.
  • Choi S., Lew K.L., Xiao H., Herman-Antosiewicz A., Xiao D., Brown C.K., Singh S.V. (2007) Apoptosis induction by broccoli-derived cancer chemopreventive agent sulforaphane is regulated by IAP family proteins and Apaf-1. Carcinogenesis 28: 151-162.
  • Kedzierska B., Szambowska A., Herman-Antosiewicz A., Lee D., Busby S., Wegrzyn G., Thomas M. (2007) The C-terminal domain of the Escherichia coli RNA polymerase alpha subunit plays a role in the CI-dependent activation of the bacteriophage lambda pM promoter. Nucleic Acids Res. 35: 2311-20.
  • Herman-Antosiewicz A., Johnson D.A., Singh S.V. (2006) Sulforaphane causes autophagy to inhibit release of cytochrom c and apoptosis in human prostate cancer cells. Cancer Res. 66: 5828-5835.
  • Antosiewicz J., Herman-Antosiewicz A., Marynowski S.W., Singh S.V. (2006) c-Jun NH2-Terminal Kinase Regulates Diallyl Trisulfide-induced Generation of Reactive Oxygen Species and Cell Cycle Arrest in Human Prostate Cancer Cells. Cancer Res. 66: 5379-5386.
  • Xiao D., Li M.F., Herman-Antosiewicz A., Antosiewicz J., Xiao H., Lew K.L., Zeng Y., Marynowski S.W., Singh S. V. (2006) Diallyl trisulfide inhibits angiogenic features of human umbilical vein endothelial cells by causing AKT inactivation and down-regulation of VEGF and VEGF-R2. Nutrition and Cancer 55: 94-107.