Dr Alicja Węgrzyn (PhD, DSc)

Scientific interests:

• Mechanisms of plasmids and bacteriophages replication
  
• Regulation of gene expression in bacterial cells
  
• Human genetic diseases
  

Publications:

• Łoś J.M., Łoś M., Węgrzyn A., Węgrzyn G. (2010) Hydrogen peroxide-mediated induction of the Shiga toxin-converting lambdoid prophage ST2-8624 in Escherichia coli O157:H7. FEMS Immunology and Medical Microbiology, przyjęta do druku.
  
• Łoś J.M., Łoś M., Węgrzyn G., Węgrzyn A. (2009) Differential efficiency of induction of various lambdoid prophages responsible for production of Shiga toxins in response to different induction agents. Microbial Pathogenesis, 47, 289-298.
  
• Nejman B., Łoś J.M., Łoś M., Węgrzyn G., Węgrzyn A. (2009) Plasmids derived from lambdoid bacteriophages as models for studying replication of mobile genetic elements responsible for production of Shiga toxins by pathogenic Escherichia coli strains. Journal of Molecular Microbiology and Biotechnology, 17, 211-220.
  
• Wang Z., Jin L., Yuan Z., Węgrzyn G., Węgrzyn A. (2009) Classification of plasmid vectors using replication origin, selection marker and promoter as criteria. Plasmid, 61, 47-51.
  
• Piotrowska E., Jakóbkiewicz-Banecka J., Tylki-Szymańska A., Czartoryska B., Węgrzyn A., Węgrzyn G. (2009) Correlation between severity of mucopolysaccharidoses and combination of the residual enzyme activity and efficiency of glycosaminoglycan synthesis. Acta Paediatrica, 98, 743-749.
  
• Łoś J.M., Łoś M., Węgrzyn A., Węgrzyn G. (2008) Role of the bacteriophage lambda exo-xis region in the virus development. Folia Microbiologica, 53, 443-450.
  
• Łoś J.M., Golec P., Węgrzyn G., Węgrzyn A., Łoś M. (2008) Simple method for plating Escherichia coli bacteriophages forming very small plaques or no plaques under standard conditions. Applied and Environmental Microbiology, 74, 5113-5120.
  
• Piotrowska E., Jakóbkiewicz-Banecka J., Tylki-Szymańska A., Liberek A., Maryniak A., Malinowska M., Czartoryska B., Puk E., Kloska A., Liberek T., Barańska S., Węgrzyn A., Węgrzyn G. (2008) Genistin-rich isoflavone extract in substrate reduction therapy for Sanfilippo syndrome: an open-label, pilot study in 10 pediatric patients. Current Therapeutic Research Clinical and Experimental, 69, 166-179.
  
• Węgrzyn G., Węgrzyn A. (2008) Is tRNA only a translation factor or also a regulator for other processes? Journal of Applied Genetics, 49, 115-122.
  
• Malinowska M., Jakóbkiewicz-Banecka J., Kloska A., Tylki-Szymańska A., Czartoryska B., Piotrowska E., Węgrzyn A., Węgrzyn G. (2008) Abnormalities in the hair morphology of patients with some but not all types of mucopolysaccharidoses. European Journal of Pediatrics, 167, 203-209.
  
• Wang Z., Li Jin L., Węgrzyn G., Węgrzyn A. (2008) Screening of the osmotic pressure-inducible promoter regions from the whole genome of Escherichia coli by using a novel cloning method. Biotechnology Letters, 30, 707-711.
  
• Jakóbkiewicz-Banecka J., Węgrzyn A., Węgrzyn G. (2007) Substrate deprivation therapy: a new hope for patients suffering from neuronopathic forms of inherited lysosomal storage diseases. Journal of Applied Genetics, 48, 383-388.