dr Grażyna Konopa

Zainteresowania naukowe:

Publikacje:

• Wysocka A., Konopa G., Węgrzyn G., Wróbel B. (2006) Genomic DNA hybridization as an attempt to evaluate phylogenetic relationships of Ostracoda. Crustaceana, 79, 1309-1322.
  
• Ulanowska K., Tkaczyk A., Konopa G., Węgrzyn G. (2006) Differential antibacterial activity of genistein arising from global inhibition of DNA, RNA and protein synthesis in some bacterial strains. Archives of Microbiology, 184, 271-278
  
• Kloska A., Bohdanowicz J., Konopa G., Tylki-Szymańska A., Jakóbkiewicz-Banecka J., Czartoryska B., Liberek A., Węgrzyn A., Węgrzyn G. (2005) Changes in hair morphology of mucopolysaccharidosis I patients treated with recombinant human-iduronidase (laronidase, Aldurazyme). American Journal of Medical Genetics, 139A, 199-203
  
• Ulanowska K., Tkaczyk A., Konopa G., Węgrzyn G. (2005) Differential antibacterial activity of genistein arising from global inhibition of DNA, RNA and protein synthesis in some bacterial strains. Archives of Microbiology, 184, 271-278
  
• Słomińska M., Konopa G., Barańska S., Węgrzyn G., Węgrzyn A.(2003) Interplay between DnaA and SeqA proteins during regulation of bacteriophage lambda p_R promoter activity. Journal of Molecular Biology, 329, 59-68
  
• Słomińska M., Konopa G., Ostrowska J., Kędzierska B., Węgrzyn G., Węgrzyn A. (2003) SeqA-mediated stimulation of a promoter activity by facilitating functions of a transcription activator. Molecular Microbiology, 47, 1669-1679
  
• Barańska S., Konopa G., Węgrzyn G. (2002) Directionality of lambda plasmid DNA replication carried out by the heritable replication complex. Nucleic Acids Research, 30, 1176-1181
  
• Słomińska M., Konopa G., Węgrzyn G., Czyż A. (2002) Impaired chromosome partitioning and synchronisation of DNA replication initiation in a Vibrio harveyi insertional mutant in the cgtA gene coding for a common GTP-binding protein. Biochemical Journal, 362, 579-584
  
• Słomińska M., Węgrzyn A., Konopa G., Skarstad K., Węgrzyn G. (2001) SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor. Molecular Microbiology, 40, 1371-1380
  
• Glinkowska M., Konopa G., Węgrzyn A., Herman-Antosiewicz A., Weigel C., Seitz H., Messer W., Węgrzyn G. (2001) The double mechanism of incompatibility between lambda plasmids and Escherichia coli dnaA(ts) host cells. Microbiology, 147, 1923-1928
  
• Barańska S., Gabig M., Węgrzyn A., Konopa G., Herman-Antosiewicz A., Hernandez P., Schvartzman J.B., Helinski D.R., Węgrzyn G.(2001) Regulation of the switch from early to late bacteriophage lambda DNA replication mode. Microbiology, 147, 535-547
  
• Czyż A., Zielke R., Konopa G., Węgrzyn G. (2001) A Vibrio harveyi insertional mutant in the cgtA (obg, yhbZ) gene, whose homologues are present in diverse organisms ranging from bacteria to humans and are essential genes in many bacterial species. Microbiology, 147, 183-191
  
• Konopa G., Barańska S., Węgrzyn A., Węgrzyn G. (2000) Bacteriophage and host mutants causing the rolling-circle lambda-DNA replication early after infection. FEBS Letters, 472, 217-220
  
• Jakimowicz D., Majka J., Konopa G., Węgrzyn G., Messer W., Schrempf H., Zakrzewska-Czerwińska J. (2000) Architecture of the Sterptomyces lividans DnaA protein-replication origin complexes. Journal of Molecular Biology, 298, 351-364
  
• Jakimowicz D., Majka J., Lis B., Konopa G., Węgrzyn G., Messer W., Schrempf H., Zakrzewska-Czerwińska J. (2000) Structure and regulation of the dnaA promoter region of three Streptomyces species. Molecular and General Genetics, 262, 1093-1102
  
• Konopa G., Szalewska-Pałasz A., Schmidt A., Śrutkowska S., Messer W., Węgrzyn G. (1999) The presence of two DnaA-binding sequences is required for efficient interaction of the Escherichia coli DnaA protein with each particular weak DnaA box region. FEMS Microbiology Letters, 174, 25-31
  
• Szalewska-Pałasz A., Weigel C., Speck C., Śrutkowska S., Konopa G., Lurz R., Marszałek J., Taylor K., Messer W., Węgrzyn G.(1998) Interaction of the Escherichia coli DnaA protein with bacteriophage lambda DNA. Molecular and General Genetics, 259, 679-688
  
• Śrutkowska S., Konopa G., Węgrzyn G. (1998) A method for isolation of plasmid DNA replication intermediates from unsynchronized bacterial cultures for electron microscopy analysis. Acta Biochimica Polonica, 45, 233-240
  
• Taylor K., Węgrzyn G., Węgrzyn A., Szalewska-Pałasz A., Herman A., Obuchowski M., Śrutkowska S., Konopa G. (1996) Escherichia coli initiator protein DnaA, cell cycle, and control of lambda plasmid replication. Bulletin of the Polish Academy of Sciences, Biological Sciences, 44, 225-230
  
• Węgrzyn G., Węgrzyn A., Konieczny I., Bielawski K., Konopa G., Obuchowski M., Helinski D.R., Taylor K. (1995) Involvement of the host initiator function dnaA in the replication of coliphage lambda. Genetics, 139, 1469-1481